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Anti-SLC22A2 Antibody 9A2
Also for SLC22A2 (NM_003058)
||0.5-1mg/ml (lot dependent)
|Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer|
|Affinity purified (Protein A or G Sepharose)
|Homo sapiens solute carrier family 22 (organic cation transporter), member 2 (SLC22A2)|
|This monoclonal 9A2 antibody recognizes human and mouse Oct2, a transcription factor that binds conserved octamer DNA motifs within immunoglobulin promoters. The structure of the Oct2 protein consists of an amino terminal glutamine-rich domain, a central POU homeodomain and a carboxy terminal transactivation domain. Predominantly expressed in the nucleus of B cells, Oct2 has also been found in activated T cells and a subset of myeloid cells. Based on knock-out studies, expression is not required for B cell commitment but is required for maturation. In addition to developmental expression, Oct2 has been associated with neoplasm and maybe a useful tool for characterization of DLBCL and classical Hodgkin?? disease.|
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Ramos cell line lysates prepared under reducing conditions were resolved by SDS-PAGE then immunoblotted with 3 ug/ml of Anti-Human/Mouse OCT2 Purified. Bands were visualized using Anti-Rat IgG HRP.