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Home Antibody All anti-SKIL antibodies

Anti-SKIL TRUEMAB Antibody Clone 2C9

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA800172
  • SKIL mouse monoclonal antibody,clone 2C9
  • FREE positive control: HEK293T cell transient overexpression lysate (LC417307) , 20ug
100ul 325 In Stock
CF800172
  • Carrier-free (BSA/glycerol-free) SKIL mouse monoclonal antibody,clone 2C9
100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(1)
IHC(5)

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 307-684 of human SKIL (NP_005405) produced in E.coli.
Clone NameClone 2C9 IsotypeIgG1
Species ReactivityHuman Concentration1.00 mg/ml
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:500, IHC 1:150,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens SKI-like oncogene (SKIL), transcript variant 1
Alternative NameSNO; SnoA; SnoI; SnoN
Database LinkNP_005405
FunctionThe protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].
Related Pathway
TGF Beta Signaling Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SKIL (RC209251, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SKIL.
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-SKIL mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA800172)
IHC Image
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-SKIL mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA800172)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-SKIL mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA800172)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-SKIL mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA800172)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-SKIL mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA800172)

 

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