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Home Antibody All anti-SIRT5 antibodies

Anti-SIRT5 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA324180
  • Anti-SIRT5 Rabbit Polyclonal Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC434135) , 20ug
100ul 325 2-3 Weeks
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WB(1)
IHC(1)

OriGene Data

ImmunogenSynthetic peptide corresponding to a region derived from 229-242 amino acids of Human sirtuin 5
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.9mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsELISA: 1:1000-5000, WB: 1:500-2000, IHC: 1:25-100
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens sirtuin 5 (SIRT5), transcript variant 4
Alternative NameSIR2L5
Database LinkNP_001229756
FunctionThis gene encodes a member of the sirtuin family of proteins; homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however; yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in multiple transcript variants.
Related Pathway

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WB Image
Predicted band size: 22 kDa . Positive control: Mouse heart tissue lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 10 seconds)
IHC Image
Predicted cell location: Cytoplasm. Positive control: Human breast cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded human breast cancer tissue using SIRT5 antibody at dilution 1/25, on the right is treated with the synthetic peptide. (Original magnification:x200)

 

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