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Home Antibody All anti-SAE1 antibodies

Anti-SAE1 TRUEMAB Antibody Clone OTI1G8

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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SKU Description Amount Price Availability*  
TA506071
  • SAE1 mouse monoclonal antibody, clone OTI1G8 (formerly 1G8)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401688) , 20ug Explanation
100ul $379 In Stock
CF506071
  • Carrier-free (BSA/glycerol-free) SAE1 mouse monoclonal antibody, clone OTI1G8 (formerly 1G8)
100ug $450 8-10 Days

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(1)
IHC(7)
IF(2)

OriGene Data

ImmunogenFull length human recombinant protein of human SAE1(NP_005491) produced in HEK293T cell.
Clone NameClone OTI1G8 IsotypeIgG2b
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC, IF Suggested Dilutions WB 1:4000, IHC 1:150, IF 1:100,
Predicted MW Explanation 38.3 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens SUMO1 activating enzyme subunit 1 (SAE1), transcript variant 1
Alternative NameAOS1; HSPC140; SUA1; UBLE1A
Database LinkNP_005491
Entrez Gene 10055 Human
FunctionPosttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010].
Related Pathway Ubiquitin mediated proteolysis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SAE1 (RC201820, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SAE1.
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-SAE1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506071)
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Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-SAE1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506071)
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Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-SAE1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506071)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-SAE1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506071)
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Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-SAE1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506071)
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Immunohistochemical staining of paraffin-embedded Human prostate tissue within the normal limits using anti-SAE1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506071)
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Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-SAE1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506071)
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Anti-SAE1 mouse monoclonal antibody (TA506071) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SAE1(RC201820).
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Immunofluorescent staining of HeLa cells using anti-SAE1 mouse monoclonal antibody (TA506071).
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