S100P is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and they are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100P, in addition to binding Ca2+, also binds Zn2+ and Mg2+. It may play a role in the etiology of prostate cancer (1).
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