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Home Antibody All anti-RPS6KB1 antibodies

Anti-RPS6KB1 TRUEMAB Antibody Clone OTI6B2

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA502929 RPS6KB1 (S6K) mouse monoclonal antibody, clone OTI6B2 (formerly 6B2) 100ul
30ul
$379 In Stock
LC401097 RPS6KB1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF502929 Carrier-free (BSA/glycerol-free) RPS6KB1 mouse monoclonal antibody, clone OTI6B2 (formerly 6B2) 100ug $450 3-4 weeks
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WB(3)
IHC(1)
IF(1)
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Also for RPS6KB1 (NM_003161)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human RPS6KB1(NP_003152) produced in HEK293T cell.
Clone NameClone OTI6B2 IsotypeIgG1
Species ReactivityHuman , Dog , Monkey , Mouse Concentration0.7 mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB 1:500~2000, IHC 1:150, IF 1:100,
Predicted MW Explanation 59 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens ribosomal protein S6 kinase, 70kDa, polypeptide 1 (RPS6KB1), transcript variant 1
Alternative Namep70 S6KA; p70(S6K)-alpha; p70-alpha; p70-S6K; PS6K; S6K; S6K-beta-1; S6K1; STK14A
Database LinkNP_003152
Entrez Gene 6198 Human
Entrez Gene 72508 Mouse
Entrez Gene 711979 Monkey
Entrez Gene 480580 Dog
FunctionThis gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized. [provided by RefSeq].
Related PathwayProtein KinaseDruggable Genome ErbB signaling pathwaymTOR signaling pathwayTGF-beta signaling pathwayFc gamma R-mediated phagocytosisInsulin signaling pathwayAcute myeloid leukemiaMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RPS6KB1 (RC217324, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RPS6KB1.
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Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-RPS6KB1 monoclonal antibody.
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Western blot analysis of extracts (10ug) from 9 Human tissue by using anti-RPS6KB1 monoclonal antibody at 1:200 (1: Testis; 2: Omentum; 3: Uterus; 4: Breast; 5: Brain; 6: Liver; 7: Ovary; 8: Thyroid gland; 9: colon).
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Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-RPS6KB1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502929)
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Anti-RPS6KB1 mouse monoclonal antibody (TA502929) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RPS6KB1(RC217324).
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