Home Antibody All anti-RPS6KB1 antibodies
Also for RPS6KB1 (NM_003161)
|This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human RPS6KB1.|
||WB: 1:50~100; IHC: 1:50-100; ELISA: 1: 1,000;
|Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.|
|Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. (Protein A or G Sepharose)
|Homo sapiens ribosomal protein S6 kinase, 70kDa, polypeptide 1 (RPS6KB1), transcript variant 1|
|p70 S6KA; p70(S6K)-alpha; p70-alpha; p70-S6K; PS6K; S6K; S6K-beta-1; S6K1; STK14A|
|This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding the gene for RPS6KB1 and overexpression of this kinase are seen in some breast cancer cell lines.|
TGF Beta Signaling Pathway
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(LEFT) Western blot analysis of anti-RPS6KB1 Antibody (Center) Pab in Jurkat and 293 cell line lysates. RPS6KB1(arrow) was detected using the purified Pab. (RIGHT)Western blot analysis of anti-RPS6KB1 Antibody (Center) Pab in 293 cell line lysates transiently transfected with the RPS6KB1 gene (2ug/lane). RPS6KB1(arrow) was detected using the purified Pab (1:60 dilution).
Formalin-fixed and paraffin-embedded human breast carcinoma reacted with RPS6KB1 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.