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Home Antibody All anti-RIPK2 antibodies

Anti-RIPK2 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA306013 Rabbit Polyclonal RICK Antibody 100ug $325 3-7 Days
LC418408 RIPK2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for RIPK2 (NM_003821)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenRICK antibody was raised against a peptide corresponding to amino acids 508 to 522 of human origin .
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 - 2 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens receptor-interacting serine-threonine kinase 2 (RIPK2)
Alternative NameCARD3; CARDIAK; CCK; GIG30; RICK; RIP2
Database LinkNP_003812
Entrez Gene 8767 Human
FunctionApoptosis is mediated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. DD-containing serine/threonine kinase RIP regulates Fas-induced apoptosis. A novel CARD-containing serine/threonine kinase was recently identified and designated RICK/RIP2/CARDIAK for RIP-like interacting CLARP kinase, receptor interacting protein-2, and CARD-containing ICE associated kinase, respectively, (1-3). RICK contains an N-terminal kinase catalytic domain and a C-terminal CARD domain. Overexpression of RICK induced apoptosis and activation of NF-kappaB and JNK. RICK interacts with members of the TRAF family, CLARP and caspase-1. Thus, RICK represents a novel kinase that regulates TNF and Fas induced-apoptosis and that is involved in the generation of proinflammatory cytokine IL-1b. The messenger RNA of RICK is expressed in multiple human tissues (1).
Related PathwayProtein KinaseDruggable Genome NOD-like receptor signaling pathwayNeurotrophin signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of RICK in A431 cell lysate with RICK antibody at (A) 1 and (B) 2 µg/ml.

IF Image
Immunocytochemistry of RICK in K562 cells with RICK antibody at 5 µg/ml

IF Image
Immunofluorescence of RICK in K562 cells with RICK antibody at 20 ug/mL.


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