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Home Antibody All anti-RIMS3 antibodies

Anti-RIMS3 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA306527 Rabbit Polyclonal Rim3 Antibody 100ug $325 3-7 Days
LC415065 RIMS3 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for RIMS3 (NM_014747)
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OriGene Data

ImmunogenRim3 antibody was raised against a 17 amino acid peptide from near the amino terminus of human Rim3.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 ug/ml, IHC: 2.5 ug/ml, IF: 5 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens regulating synaptic membrane exocytosis 3 (RIMS3)
Alternative NameNIM3; RIM3
Database LinkNP_055562
Entrez Gene 9783 Human
Entrez Gene 242662 Mouse
FunctionRab3-interacting molecules (RIMs) are synaptic proteins are synaptic proteins necessary for neural transmission and plasticity. While both Rim1 and Rim 2 are thought to be effector proteins for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner, less is known of Rim3. Expression of Rim3 in PC12 cells induced a significant increase in calcium-triggered exocytosis, with no appreciable change in the baseline release, suggesting that it plays a role in the regulation of exocytosis. Rim3 protein localizes primarily to neuronal dendrites and the postsynaptic densities, as opposed to Rim1 which is found in presynapse locations, indicating that Rim3 may contribute to synapse transmission and plasticity. This antibody is predicted to have no cross-reactivity to other Rim proteins.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of Rim3 in human brain tissue lysate with Rim3 antibody at 1 ug/ml in the (A) absence and (B) presence of blocking peptide.
Immunohistochemistry of Rim3 in human brain tissue with Rim3 antibody at 2.5 ug/ml.


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