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Home Antibody All anti-RGS10 antibodies

Anti-RGS10 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA308469 Rabbit polyclonal antibody to RGS10 (regulator of G-protein signaling 10) 100ul $325 3-7 Days
LC423865 RGS10 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)
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Also for RGS10 (NM_001005339)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 1 and 173 of RGS10 (Uniprot ID#O43665)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse) Concentration0.7mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsIHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 21kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (92%)

Reference Data

Target NameHomo sapiens regulator of G-protein signaling 10 (RGS10), transcript variant 1
Alternative NameOTTHUMP00000020597; OTTHUMP00000069158; regulator of G-protein signalling 10; regulator of G-protein signaling 10
Database LinkNP_001005339
Entrez Gene 6001 Human
Entrez Gene 67865 Mouse
FunctionRegulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. Regulator of G protein signaling 10 protein is localized in the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample (30 ug of whole cell lysate). A: A431 . 12% SDS PAGE. TA308469 diluted at 1:1000.
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Immunohistochemical analysis of paraffin-embedded Breast ca, using RGS10(TA308469) antibody at 1:250 dilution.
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