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Anti-REL Antibody EPR2559(2)


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SKU Description Amount Price Availability*  
  • Rabbit monoclonal antibody against c-Rel(clone EPR2559(2))
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419012) , 20ug Explanation
100ul $325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human c-Rel was used as an immunogen.
Clone NameEPR2559(2) IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:10000 - 1:50000; IP: 1:10 - 1:100
BufferpH: 7.40Preservative: 0.01% Sodium azide; Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for Flow Cyt,ICC/IF or IHC-P.

Reference Data

Target NameHomo sapiens v-rel avian reticuloendotheliosis viral oncogene homolog (REL), transcript variant 1
Alternative NameC-Rel
Database LinkNP_002899
Entrez Gene 5966 Human
Functionc-Rel is a member of the nuclear factor kB (NF-kB) transcription factor family. The NF-kB family of dimeric transcription factors consists of four other mammalian members, RelA (p65), RelB, NF-kB1 (p105/p50) and NFkB2 (p100/p52) and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. c-Rel is a proto-oncogene that may play a role in differentiation and lymphopoiesis. C-Rel form different dimmer combinations that act as transcriptional activators of repressors (1). Findings indicate that RelA and c-Rel control the development of the epidermis and associated appendages during embryogenesis and regulate epidermal homeostasis in a postnatal environment through the suppression of innate immune-mediated inflammation (2).
Related PathwayTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-c-Rel antibody [EPR2559(2)]; All lanes : Anti-c-Rel antibody [EPR2559(2)] at 1/10000 dilution.Lane 1 : Daudi cell lysates.Lane 2 : HuT-78 cell lysates.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 68 kDa.


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