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Anti-REL Antibody EPR2559(2)
|A synthetic peptide corresponding to residues in human c-Rel was used as an immunogen.|
||Tissue culture supernatant
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:10000 - 1:50000; IP: 1:10 - 1:100
|pH: 7.40Preservative: 0.01% Sodium azide; Constituents: 50% Glycerol, 0.05% BSA|
|Is unsuitable for Flow Cyt,ICC/IF or IHC-P.
|Homo sapiens v-rel avian reticuloendotheliosis viral oncogene homolog (REL), transcript variant 1|
Entrez Gene 5966 Human
|c-Rel is a member of the nuclear factor kB (NF-kB) transcription factor family. The NF-kB family of dimeric transcription factors consists of four other mammalian members, RelA (p65), RelB, NF-kB1 (p105/p50) and NFkB2 (p100/p52) and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. c-Rel is a proto-oncogene that may play a role in differentiation and lymphopoiesis. C-Rel form different dimmer combinations that act as transcriptional activators of repressors (1). Findings indicate that RelA and c-Rel control the development of the epidermis and associated appendages during embryogenesis and regulate epidermal homeostasis in a postnatal environment through the suppression of innate immune-mediated inflammation (2).|
|Transcription FactorsDruggable Genome |
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Western blot - Anti-c-Rel antibody [EPR2559(2)]; All lanes : Anti-c-Rel antibody [EPR2559(2)] at 1/10000 dilution.Lane 1 : Daudi cell lysates.Lane 2 : HuT-78 cell lysates.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 68 kDa.