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Home Antibody All anti-RASSF1 antibodies

Anti-RASSF1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308998
  • Rabbit polyclonal antibody to RASSF1 (Ras association (RalGDS/AF-6) domain family member 1)
100ul 325 3-7 Days
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WB(1)
IF(1)
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Also for RASSF1 (NM_170714)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 50 and 344 of RASSF1 (Uniprot ID#Q9NS23)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Rat) Concentration1mg/ml
Guaranteed Application *WB, IF Suggested DilutionsICC/IF:1:100-1:1000; WB:1:500-1:3000
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (91%), Rat (91%)

Reference Data

Target NameHomo sapiens Ras association (RalGDS/AF-6) domain family member 1 (RASSF1), transcript variant D
Alternative Name123F2; NORE2A; RASSF1A; RDA32; REH3P21
Database LinkNP_733832
Entrez Gene 11186 Human
Entrez Gene 56289 Mouse
Entrez Gene 363140 Rat
FunctionThis gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq]
Related PathwayDruggable Genome Pathways in cancerBladder cancerNon-small cell lung cancer

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample(30 ug whole cell lysate). A:293T. 12% SDS PAGE. TA308998diluted at 1:500
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using RASSF1(TA308998) antibody at 1:100 dilution.

 

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