Home Antibody All anti-RASSF1 antibodies
Also for RASSF1 (NM_170714)
|Recombinant fragment corresponding to a region within amino acids 50 and 344 of RASSF1 (Uniprot ID#Q9NS23)|
|Human (Predicted: Mouse, Rat)
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Mouse (91%), Rat (91%)
|Homo sapiens Ras association (RalGDS/AF-6) domain family member 1 (RASSF1), transcript variant D|
|123F2; NORE2A; RASSF1A; RDA32; REH3P21|
Entrez Gene 11186 Human
Entrez Gene 56289 Mouse
Entrez Gene 363140 Rat
|This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq]|
|Druggable Genome Pathways in cancerBladder cancerNon-small cell lung cancer|
* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
Sample(30 ug whole cell lysate). A:293T. 12% SDS PAGE. TA308998diluted at 1:500
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using RASSF1(TA308998) antibody at 1:100 dilution.