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Home Antibody All anti-RASGRF1 antibodies

Anti-RASGRF1 Antibody EPR1790(2)

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307851
  • Rabbit monoclonal antibody against RasGRF1(clone EPR1790(2))
  • FREE positive control: HEK293T cell transient overexpression lysate (LC419036) , 20ug
100ul 325 3-7 Days
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WB(1)
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Also for RASGRF1 (NM_002891)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus in human RasGRF1 was used as an immunogen.
Clone NameEPR1790(2) IsotypeTissue culture supernatant
Species ReactivityHuman, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000
BufferDoes not react with Mouse. Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
Purification pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for Flow Cyt,ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens Ras protein-specific guanine nucleotide-releasing factor 1 (RASGRF1), transcript variant 1
Alternative NameCDC25; CDC25L; GNRP; GRF1; GRF55; H-GRF55; PP13187; ras-GRF1
Database LinkNP_002882
FunctionRasGRF1 is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from the Ras protein. The studies of the similar RasGRF1 in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by RasGRF1 may be important for long-term memory.
Related Pathway
Focal Adhesion
MAPK signaling pathway
Signaling by GPCR

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WB Image
Western blot - RASGRF1 antibody [EPR1790(2)]; All lanes : Anti-RASGRF1 antibody [EPR1790(2)] at 1/1000 dilution.Lane 1 : Human hippocampus lysate.Lane 2 : Human hypothalamus lysate.Lane 3 : Human midbrain lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 145 kDa.

 

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