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Anti-RASGRF1 Antibody EPR1790(2)


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SKU Description Amount Price Availability*  
  • Rabbit monoclonal antibody against RasGRF1(clone EPR1790(2))
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419036) , 20ug Explanation
100ul $325 3-7 Days
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Also for RASGRF1 (NM_002891)
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus in human RasGRF1 was used as an immunogen.
Clone NameEPR1790(2) IsotypeIgG
Species ReactivityRat, Human (Does not react with: Mouse) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000
BufferpH: 7.20; Preservative: 0.01% Sodium azide; Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for Flow Cyt,ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens Ras protein-specific guanine nucleotide-releasing factor 1 (RASGRF1), transcript variant 1
Alternative NameCDC25; CDC25L; GNRP; GRF1; GRF55; H-GRF55; PP13187; ras-GRF1
Database LinkNP_002882
Entrez Gene 5923 Human
Entrez Gene 192213 Rat
FunctionRasGRF1 is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from the Ras protein. The studies of the similar RasGRF1 in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by RasGRF1 may be important for long-term memory.
Related PathwayDruggable Genome MAPK signaling pathwayFocal adhesion

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - RASGRF1 antibody [EPR1790(2)]; All lanes : Anti-RASGRF1 antibody [EPR1790(2)] at 1/1000 dilution.Lane 1 : Human hippocampus lysate.Lane 2 : Human hypothalamus lysate.Lane 3 : Human midbrain lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 145 kDa.


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