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Anti-RASGRF1 Antibody EPR1790(2)
Also for RASGRF1 (NM_002891)
|A synthetic peptide corresponding to residues on the C-terminus in human RasGRF1 was used as an immunogen.|
|Rat, Human (Does not react with: Mouse)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000
|pH: 7.20; Preservative: 0.01% Sodium azide; Constituents: 50% Glycerol, 0.05% BSA|
|Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
|Homo sapiens Ras protein-specific guanine nucleotide-releasing factor 1 (RASGRF1), transcript variant 1|
|CDC25; CDC25L; GNRP; GRF1; GRF55; H-GRF55; PP13187; ras-GRF1|
Entrez Gene 5923 Human
Entrez Gene 192213 Rat
|RasGRF1 is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from the Ras protein. The studies of the similar RasGRF1 in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by RasGRF1 may be important for long-term memory.|
|Druggable Genome MAPK signaling pathwayFocal adhesion|
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Western blot - RASGRF1 antibody [EPR1790(2)]; All lanes : Anti-RASGRF1 antibody [EPR1790(2)] at 1/1000 dilution.Lane 1 : Human hippocampus lysate.Lane 2 : Human hypothalamus lysate.Lane 3 : Human midbrain lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 145 kDa.