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Anti-RASGRF1 Antibody EPR1790(2)
Also for RASGRF1 (NM_002891)
|A synthetic peptide corresponding to residues on the C-terminus in human RasGRF1 was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000
|Does not react with Mouse. Is unsuitable for Flow Cyt,ICC,IHC-P or IP.|
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
|Homo sapiens Ras protein-specific guanine nucleotide-releasing factor 1 (RASGRF1), transcript variant 1|
|CDC25; CDC25L; GNRP; GRF1; GRF55; H-GRF55; PP13187; ras-GRF1|
|RasGRF1 is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from the Ras protein. The studies of the similar RasGRF1 in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by RasGRF1 may be important for long-term memory.|
MAPK signaling pathway
Signaling by GPCR
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Western blot - RASGRF1 antibody [EPR1790(2)]; All lanes : Anti-RASGRF1 antibody [EPR1790(2)] at 1/1000 dilution.Lane 1 : Human hippocampus lysate.Lane 2 : Human hypothalamus lysate.Lane 3 : Human midbrain lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 145 kDa.