Homo sapiens receptor-associated protein of the synapse (RAPSN), transcript variant 1
Synonyms:
RAPSYN; RNF205
Immunogen
Peptide with sequence YQSNQTEKALQVWTK-C, from the N-Terminus of the protein sequence according to NP_005046.2; NP_116034.2.
Buffer
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Clone Name
Isotype
Goat IgG
Species Reactivity
Human, Mouse, Rat
Concentration
0.5 mg/ml
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing. (Protein A or G Sepharose)
Guaranteed Application *
WB
Suggested Dilutions
WB: 0.3-1ug/ml.
Background
This protein belongs to a family of proteins that are receptor associated proteins of the synapse. It contains a conserved cAMP-dependent protein kinase phosphorylation site. It is believed to play some role in anchoring or stabilizing the nicotinic acetylcholine receptor at synaptic sites. It may link the receptor to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Two splice variants have been identified for this gene.
Related Pathway
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TA305694 (0.5µg/ml) staining of Human Skeletal Muscle lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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