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Home Antibody All anti-RAD51 antibodies

Anti-RAD51 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA322085
  • Anti-RAD51 Rabbit Polyclonal Antibody
100ul 325 2-3 Weeks
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IHC(2)

OriGene Data

ImmunogenSynthetic peptide corresponding to a region derived from 301-312 amino acids of Human RAD51 homolog (S. cerevisiae)
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1.1mg/ml
Guaranteed Application *IHC Suggested DilutionsELISA: 1:1000-5000, IHC: 1:25-100
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens RAD51 recombinase (RAD51), transcript variant 2
Alternative NameBRCC5; HRAD51; HsRad51; HsT16930; MRMV2; RAD51A; RECA
Database LinkNP_597994
Entrez Gene 5888 Human
Entrez Gene 19361 Mouse
Entrez Gene 499870 Rat
FunctionThe protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51; and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52; and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2; which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene.
Related PathwayStem cell - PluripotencyTranscription FactorsDruggable Genome Homologous recombinationPathways in cancerPancreatic cancer

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

IHC Image
Predicted cell location: Cytoplasm. Positive control: Human esophagus and cervical cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded human esophagusl cancer tissue using RAD51 antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification:x 200)
IHC Image
Predicted cell location: Cytoplasm. Positive control: Human esophagus and cervical cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded human cervical cancer tissue using RAD51 antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification:x200)

 

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