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Home Antibody All anti-RAB4A antibodies

Anti-RAB4A Antibody EPR3042

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307279
  • Rabbit monoclonal antibody against Rab4(clone EPR3042)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401450) , 20ug
100ul 325 3-7 Days
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WB(1)
IF(1)
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Also for RAB4A (NM_004578)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Rab4 was used as an immunogen.
Clone NameEPR3042 IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsWB: 1:2000 - 1:10000; FC: 1:150; ICC/IF: 1:100 - 1:250
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for IHC-P or IP.

Reference Data

Target NameHomo sapiens RAB4A, member RAS oncogene family (RAB4A), transcript variant 1
Alternative NameHRES-1; HRES-1/RAB4; HRES1; RAB4
Database LinkNP_004569
FunctionRab proteins constitute a family of GTP-binding proteins that are located in distinct intracellular compartments and play a role in the regulation of vesicular trafficking (1). The small GTPase Rab4 is associated with early endocytic compartments and regulates receptor recycling from early endosomes. It has been proposed that Rab4 assists in the docking of transport vesicles en route from early endosomes to recycling endosomes (2). Rab4 (along with Rab5 and Rab11) regulate sequential transport steps along the endocytic/recycling pathway, and occupy distinct membrane domains on early and recycling endosomes. It seems that divalent Rab effectors regulate protein sorting and recycling by connecting Rab domains on early endosomes (3).
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Rab4 antibody [EPR3042]; All lanes : Anti-Rab4 antibody [EPR3042] at 1/2000 dilution.Lane 1 : MCF7 cell lysates .Lane 2 : PC12 cell lysates .Lane 3 : Fetal brain cell lysates .Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 24 kDa.Observed band size : 25 kDa .
IF Image
Immunocytochemistry/ Immunofluorescence - Rab4 antibody [EPR3042]; Immunofluorescent staining of Rab4 in HeLa cells, using TA307279 at a 1/100 dilution.

 

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