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Home Antibody All anti-QPRT antibodies

Anti-QPRT TRUEMAB Antibody Clone OTI4E6

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA501522 QPRT mouse monoclonal antibody, clone OTI4E6 (formerly 4E6) 100ul $325 In Stock
LC402307 QPRT HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF501522 Carrier-free (BSA/glycerol-free) QPRT mouse monoclonal antibody, clone OTI4E6 (formerly 4E6) 100ug $450 3-4 weeks
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WB(2)
IHC(3)
FC(1)

OriGene Data

ImmunogenFull length human recombinant protein of human QPRT (NP_055113) produced in HEK293T cell.
Clone NameClone OTI4E6 IsotypeIgG1
Species ReactivityHuman Concentration0.83 mg/ml
Guaranteed Application *WB, IHC, FC Suggested DilutionsWB 1:500~2000, IHC 1:150, FLOW 1:100
Predicted MW Explanation 30.6 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens quinolinate phosphoribosyltransferase (QPRT)
Alternative NameHEL-S-90n; QPRTase
Database LinkNP_055113
Entrez Gene 23475 Human
FunctionThis gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.
Related Pathway Nicotinate and nicotinamide metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY QPRT (RC202960, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-QPRT.
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Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-QPRT monoclonal antibody.
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Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-QPRT mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501522)
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Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-QPRT mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501522)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-QPRT mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501522)
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HEK293T cells transfected with either RC202960 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-QPRT antibody(TA501522), and then analyzed by flow cytometry.
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