Home Antibody All anti-Prkcb antibodies
Also for Prkcb (NM_002738)
|Synthetic peptide corresponding to the C-terminus of mouse PKC ß1 |
|Human, mouse, rat
|100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.|
|Homo sapiens protein kinase C, beta (PRKCB), transcript variant 2|
|PKC-beta; PKCB; PRKCB1; PRKCB2|
|PKC (Protein kinase C) is a calcium-dependent and phospholipid-dependent enzyme that is activated in vivo by the lipid diacylglycerol. PKC has been shown to be involved in signal transduction and various aspects of neoplastic transformation. PKC contains an amino terminal regulatory domain and a carboxy terminal catalytic domain joined by a hinge region. Cleavage of protein kinase C in vitro results in the generation of two functional fragments corresponding to these two domains. The antibody recognizes 60-75 kDa PKC ßisoforms from samples of human, mouse, rat, pig and bovine origins. A 40 kDa band can also be detected, presumably to be a shorter form of PKC isoforms.|
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Western blot analysis of PKC expression in rat kidney tissue lysate.