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Also for Prf1 (NM_005041)
|Recombinant rat perforin |
|100 µg (0.5 mg/ml) affinity purified rabbit anti-Perforin polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.|
|Homo sapiens perforin 1 (pore forming protein) (PRF1), transcript variant 1|
|FLH2; HPLH2; P1; PFN1; PFP|
|Perforin (Pore-forming protein) is originally cloned from mouse cytotoxic T-lymphocyte (CTL). It is a 555-amino acid protein with a 21-amino acid signal peptide. Perforin is a cytolytic mediator produced by killer lymphocytes, and is stored in and released by cytoplasmic granules. Perforin is involved in the killing mediated by CTL which represents an important mechanism in the immune defense against tumors and virus infection. |
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Western blot analysis of Perforin in rat kidney glomerulars.