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Home Antibody All anti-Perp antibodies

Anti-Perp Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306075
  • Rabbit Polyclonal PERP Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC411759) , 20ug
100ug 325 3-7 Days
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WB(1)
IF(1)
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Also for Perp (NM_022121)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenPERP antibody was raised against a synthetic peptide corresponding to amino acids near the carboxy terminus of human PERP, which differ from the mouse sequence by three amino acids (7-9) .
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 ug/ml, ICC: 10 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Antibody is DEAE purified

Reference Data

Target NameHomo sapiens PERP, TP53 apoptosis effector (PERP)
Alternative NamedJ496H19.1; KCP1; KRTCAP1; PIGPC1; THW
Database LinkNP_071404
FunctionThe p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 network, including Chk2 , p53R2 (2), p53AIP1 (3), Noxa (4), PIDD (5), PID/MTA2 (6), MTBP (7) and PERP (8), were identified and their genes were cloned recently. PERP, also termed PIGPC1 and THW, is a plasma membrane protein (8-10). p53 binds to the promoter of PERP and transcriptionally activates PERP gene then the translated PERP protein mediates the p53 induced apoptosis (8). The expression of PERP causes cell death. PERP is a mediator of p53 induced apoptosis. PERP has sequence similarity to PMP-22/gas3 and is a new member of the PMP-22/gas3 family (8).
Related Pathway

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WB Image
Western blot analysis of PERP expression in A431 whole cell lysates in the absence (A) and presence (B) of blocking peptide with PERP antibody at 1 ug /ml.
IF Image
Immunocytochemistry of PERP in A431 cells with PERP antibody at 10 ug/mL.

 

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