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Home Antibody All anti-PTPN7 antibodies

Anti-PTPN7 TRUEMAB Antibody clone 3B10

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA503714
  • PTPN7 (HePTP) mouse monoclonal antibody, clone 3B10
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC409137) , 20ug Explanation
100ul 379 In Stock
CF503714
  • Carrier-free (BSA/glycerol-free) PTPN7 mouse monoclonal antibody,clone 3B10
100ug $450 3-4 weeks
This antibody qualifies for Season of Giving promotion: Earn $50 Amazon gift card (use promo code SPQ12081) or donation to Cancer.org (promo code SPQ12082) with $600 purchase of UltraMAB or TrueMAB. Click for details
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WB(1)
IF(1)
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Also for PTPN7 (NM_080588)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human PTPN7(NP_542155) produced in HEK293T cell.
Clone Nameclone 3B10 IsotypeIgG2b
Species ReactivityHuman , Dog , Rat , Mouse Concentration0.72 mg/ml
Guaranteed Application *WB, IF Suggested DilutionsWB 1:500~2000, IF 1:100,
Predicted MW Explanation 44.8 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens protein tyrosine phosphatase, non-receptor type 7 (PTPN7), transcript variant 2
Alternative NameBPTP-4; HEPTP; LC-PTP; LPTP; PTPNI
Database LinkNP_542155
Entrez Gene 5778 Human
Entrez Gene 320139 Mouse
Entrez Gene 246781 Rat
Entrez Gene 607227 Dog
FunctionThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq].
Related PathwayPhosphataseDruggable Genome MAPK signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PTPN7 (RC216254, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PTPN7.
IF Image
Anti-PTPN7 mouse monoclonal antibody (TA503714) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PTPN7(RC216254).

 

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