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Home Antibody All anti-PTPN11 antibodies

Anti-PTPN11 PHOSPHO Antibody


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SKU Description Amount Price Availability*  
TA321539 Anti-PTPN11 (Phospho-Tyr542) Rabbit Polyclonal Antibody 100ul 325
2-3 Weeks
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Also for PTPN11 (NM_002834)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenPeptide sequence around phosphorylation site of tyrosine 542 (H-E-Y(p)-T-N) derived from Human SHP-2.
Clone Name IsotypeIgG
Species ReactivityHuman; Mouse; Rat Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:500-1000, IHC: 1:50-100
Predicted MW Explanation 68kDa
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens protein tyrosine phosphatase, non-receptor type 11 (PTPN11), transcript variant 1
Alternative NameBPTP3; CFC; NS1; PTP-1D; PTP2C; SH-PTP2; SH-PTP3; SHP2
Database LinkNP_002825
Entrez Gene 5781 Human
Entrez Gene 19247 Mouse
Entrez Gene 25622 Rat
FunctionActs downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus.
Related PathwayPhosphataseDruggable Genome Jak-STAT signaling pathwayNatural killer cell mediated cytotoxicityLeukocyte transendothelial migrationNeurotrophin signaling pathwayAdipocytokine signaling pathwayEpithelial cell signaling in Helicobacter pylori infectionMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Predicted band size: 68 kDa . Positive control: 293 cells treated with starvation lysate. Recommended dilution: 1/ 500-1000. (Gel: 8%SDS-PAGE Lane1: 293 cells untreated with starvation lysate Lane2: 293 cells treated with starvation lysate Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)
Predicted cell location: Cytoplasm. Positive control: Human breast carcinoma tissue. Recommended dilution: 1/ 50-100 The image on the left is immunohistochemistry of paraffin-embedded human breast carcinoma tissue using PTPN11 (Phospho-Tyr542) antibody at dilution 1/50, on the right is treated with the synthetic peptide. (Original magnification: x200)


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