Home Antibody All anti-PTP4A1 antibodies
Also for PTP4A1 (NM_003463)
| Peptide with sequence KDSNGHRNNCCIQ, from the C Terminus of the protein sequence according to NP_003454.1.|
|Test: Human. Expected from seq similarity: Human, Mouse, Rat, Dog
||ELISA: 1:2,000. WB: 1-3µg/ml.
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
| Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
|Homo sapiens protein tyrosine phosphatase type IVA, member 1 (PTP4A1)|
|HH72; PRL-1; PRL1; PTP(CAAX1); PTPCAAX1|
Entrez Gene 7803 Human
Entrez Gene 19243 Mouse
Entrez Gene 29463 Rat
Entrez Gene 481863 Dog
|The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells. [provided by RefSeq]. |
|PhosphataseDruggable Genome |
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TA302743 (1µg/ml) staining of A549 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.