OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-PRKCQ antibodies

Anti-PRKCQ Antibody EPR1488Y

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303662
  • Rabbit monoclonal antibody against PKC theta (EPR1488Y )
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC416765) , 20ug Explanation
100ul 325 3-7 Days
Add to Shopping Cart
spacer
WB(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues surrounding Tyrosine 538 of human PKC theta was used as an immunogen. This antibody detects both phosphorylated (pT538) and unphosphorylated PKC theta.
Clone NameEPR1488Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:500
Predicted MW Explanation 85 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens protein kinase C, theta (PRKCQ), transcript variant 1
Alternative NamenPKC-theta; PRKCT
Database LinkNP_006248
Entrez Gene 5588 Human
Entrez Gene 18761 Mouse
Entrez Gene 85420 Rat
FunctionProtein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. [provided by RefSeq].
Related PathwayProtein KinaseTranscription FactorsDruggable Genome Vascular smooth muscle contractionTight junctionT cell receptor signaling pathwayAdipocytokine signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - PKC theta antibody [EPR1488Y]; Anti-PKC theta antibody [EPR1488Y] at 1/500 dilution + Jurkat cell lysate at 10 ug.Secondary.HRP labeled goat anti-rabbit at 1/2000 dilution.Predicted band size : 85 kDa.Observed band size : 85 kDa.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title