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Home Antibody All anti-PRKAB1 antibodies

Anti-PRKAB1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302581
  • Goat Polyclonal Antibody against PRKAB1
  • FREE positive control: HEK293T cell transient overexpression lysate (LC416773) , 20ug
100ug $325 3-7 Days
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WB(1)
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Also for PRKAB1 (NM_006253)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenPeptide with sequence C-QHDLEANDKAPAQ, from the internal region of the protein sequence according to NP_006244.2.
Clone Name IsotypeGoat IgG
Species ReactivityHuman, Mouse, Rat, Dog Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:64,000. WB: 0.1-0.3µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Reference Data

Target NameHomo sapiens protein kinase, AMP-activated, beta 1 non-catalytic subunit (PRKAB1)
Alternative NameAMPK; HAMPKb
Database LinkNP_006244
FunctionThe protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. [provided by RefSeq].
Related Pathway

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WB Image
TA302581 (0.1µg/ml) staining of Human Liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

 

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