Home Antibody All anti-PRKAA2 antibodies
Also for PRKAA2 (NM_006252)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 29 and 480 of AMPK alpha 2|
|WB, IHC, IF
||WB:1:500-1:3000; IHC:1:500; IF:1:100-1:500;
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography. (Protein A or G Sepharose)
|Homo sapiens protein kinase, AMP-activated, alpha 2 catalytic subunit (PRKAA2)|
|AMPK; AMPK2; AMPKa2; PRKAA|
|The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq]|
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Sample (30 ug of whole cell lysate) A:NIH-3T3 ( anti-PRKAA2 antibody diluted at 1:1000)
Immunohistochemical analysis of paraffin-embedded A549 xenograft, using AMPK alpha 2(anti-PRKAA2 antibody) antibody at 1:500 dilution.
Immunofluorescence analysis of paraformaldehyde-fixed A431, using AMPK alpha 2(anti-PRKAA2 antibody) antibody at 1:200 dilution.