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Home Antibody All anti-PPP2CA antibodies

Anti-PPP2CA Antibody YE351

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300445
  • Rabbit Monoclonal Antibody against PPP2CA (Clone YE351)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419151) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for PPP2CA (NM_002715)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in N-terminus of human PP2A-alpha was used as immunogen. Predicted to cross-react with bovin and pig, based on sequence homology.
Clone NameYE351 IsotypeIgG
Species ReactivityRat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:500; IHC: 1:50-100
Predicted MW Explanation 36 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Protein A purified

Reference Data

Target NameHomo sapiens protein phosphatase 2, catalytic subunit, alpha isozyme (PPP2CA)
Alternative NamePP2Ac; PP2CA; PP2Calpha; RP-C
Database LinkNP_002706
Entrez Gene 5515 Human
Entrez Gene 24672 Rat
FunctionProtein phosphatase type 2A (PP2A) is a protein serine/threonine phosphatase that controls fundamental cellular processes, including transcription, translation, metabolism, cell growth, apoptosis, and varied other signal transduction pathways (1-3). PP2A is comprised of a core enzyme, which is made up of catalytic C and regulatory A (PR65) subunits, and a secondary regulatory B subunit. This B subunit contains four different protein families. In response to EGF or insulin, it has been shown that Src phosphorylates PP2A at Tyr307, thereby inactivating PP2A (4).
Related PathwayPhosphataseTranscription FactorsDruggable Genome Oocyte meiosisWnt signaling pathwayTGF-beta signaling pathwayTight junctionLong-term depression

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - PP2A alpha antibody [YE351]; All lanes : Anti-PP2A alpha antibody [YE351] at 1/500 dilution.Lane 1 : A431 cell lysate.Lane 2 : NIH 3T3 cell lysate.Predicted band size : 36 kDa.Observed band size : 37 kDa .
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PP2A alpha antibody [YE351]; TA300445 at a 1/50 dilution staining in human PP2A alpha catalitic subunit prostate carcinoma, using Immunohistochemistry, Paraffin Embedded Tissue.

 

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