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Home Antibody All anti-PPAPDC3 antibodies

Anti-PPAPDC3 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306887
  • Rabbit Polyclonal PPAPDC3 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC409965) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IF(1)
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Also for PPAPDC3 (NM_032728)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenPPAPDC3 antibody was raised against a 19 amino acid peptide from near the amino of terminus human PPAPDC3.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 - 2 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens phosphatidic acid phosphatase type 2 domain containing 3 (PPAPDC3)
Alternative NameC9orf67; NET39
Database LinkNP_116117
Entrez Gene 84814 Human
Entrez Gene 227721 Mouse
Entrez Gene 296635 Rat
FunctionPPAPDC3, also known as nuclear envelope transmembrane protein 39 (NET39), was initially discovered in an in silico screen for secreted or membrane proteins. It is a member of the PAP2 superfamily of phosphatases and haloperoxidases. PPAPDC3 has recently been shown to act as a negative regulator of myoblast differentiation by diminishing the activity of the mammalian target of rapamycin TOR. PPAPDC3 is highly expressed in cardiac and skeletal muscle and becomes strongly upregulated during cultured myoblast differentiation tissues. Overexpression of PPAPDC3 in myoblasts repressed myogenesis while knockdown by RNA interference promoted differentiation indicating its part in the regulatory mechanism for myogenesis.
Related PathwayTransmembrane

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of PPAPDC3 in mouse heart tissue lysate with PPAPDC3 antibody at (A) 1 and (B) 2 µg/ml.
IF Image
Immunofluorescence of PPAPDC3 in mouse heart tissue with PPAPDC3 antibody at 20 ug/mL.

 

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