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Home Antibody All anti-PON1 antibodies

Anti-PON1 Antibody EPR2892

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA307707
  • Rabbit monoclonal antibody against PON 1(clone EPR2892)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400156) , 20ug Explanation
100ul $325 3-7 Days
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WB(1)
IHC(5)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the N-terminus in human PON 1 was used as an immunogen.
Clone NameEPR2892 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsIHC: 1: 100 - 250, IP: 1 : 10 - 100, WB: 1 : 1,000 - 10,000,
Predicted MW Explanation 40 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens paraoxonase 1 (PON1)
Alternative NameESA; MVCD5; PON
Database LinkNP_000437
Entrez Gene 5444 Human
FunctionParaoxonase 1 (PON 1) is an esterase and lactonase that is synthesized in the liver and secreted into blood, associated exclusively with high density lipoproteins (HDL) (1, 3). It hydrolyzes the toxic oxon metabolites of several organophosphorous insecticides and nerve agents (2). This protein has been implicated in protection from atherosclerosis (2). PON 1 possesses both antioxidant and anti-inflammatory properties (1, 3). Protecting LDL and HDL from lipid peroxidation, PON 1 degrades specific oxidized cholesteryl esters and oxidized phospholipids contained in lipoproteins (1, 3, 4).
Related PathwaySecreted ProteinDruggable Genome Metabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - PON1 antibody [EPR2892]; All lanes : Anti-PON1 antibody [EPR2892] at 1/1000 dilution.Lane 1 : Human plasma cell lysate.Lane 2 : ovarian cancer lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit IgG at 1/2000 dilution.Predicted band size : 40 kDa.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PON1 antibody [EPR2892]; TA307707, at 1/100 dilution, staining PON1 in formalin-fixed, paraffin-embedded Human liver tissue.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-PON1 antibody [EPR2892](TA307707); TA307707 showing negative staining in Skeletal muscle tissue.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-PON1 antibody [EPR2892](TA307707); TA307707 showing negative staining in Normal colon tissue.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-PON1 antibody [EPR2892](TA307707); TA307707 showing negative staining in Normal breast tissue.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-PON1 antibody [EPR2892](TA307707); TA307707 showing negative staining in Normal brain tissue.
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