Home Antibody All anti-POLG antibodies
Also for POLG (NM_001126131)
|Recombinant fragment corresponding to a region within amino acids 779 and 1231 of DNA polymerase gamma (Uniprot ID#P54098)|
|WB, IHC, IF
||ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens polymerase (DNA directed), gamma (POLG), transcript variant 2|
|MDP1; MIRAS; MTDPS4A; MTDPS4B; PEO; POLG1; POLGA; SANDO; SCAE|
Entrez Gene 5428 Human
|Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]|
|Druggable Genome Metabolic pathways|
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Sample (30 ug of whole cell lysate). A: MCF-7. 5% SDS PAGE. TA308753 diluted at 1:1000.
DNA polymerase gamma antibody detects POLG protein by Western blot analysis. A. 50 ug Rat testis lysate/extract. 5% SDS-PAGE. DNA polymerase gamma antibody (TA308753) dilution: 1:1000.
Immunohistochemical analysis of paraffin-embedded Skeletal Muscle , using DNA polymerase gamma(TA308753) antibody(10 ug/ml).
Immunofluorescence analysis of methanol-fixed HeLa, using DNA polymerase gamma(TA308753) antibody at 1:200 dilution.