OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-POLG antibodies

Anti-POLG Antibody

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308753
  • Rabbit Polyclonal antibody to DNA polymerase gamma (polymerase (DNA directed), gamma)
100ul 325 3-7 Days
Add to Shopping Cart
WB(2)
IHC(1)
IF(1)
spacer
Also for POLG (NM_001126131)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 779 and 1231 of DNA polymerase gamma (Uniprot ID#P54098)
Clone Name IsotypeIgG
Species ReactivityHuman Concentration0.79mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 140kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens polymerase (DNA directed), gamma (POLG), transcript variant 2
Alternative NameMDP1; MIRAS; MTDPS4A; MTDPS4B; PEO; POLG1; POLGA; SANDO; SCAE
Database LinkNP_001119603
Entrez Gene 5428 Human
FunctionMitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
Related PathwayDruggable Genome Metabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate). A: MCF-7. 5% SDS PAGE. TA308753 diluted at 1:1000.
WB Image
DNA polymerase gamma antibody detects POLG protein by Western blot analysis. A. 50 ug Rat testis lysate/extract. 5% SDS-PAGE. DNA polymerase gamma antibody (TA308753) dilution: 1:1000.
IHC Image
Immunohistochemical analysis of paraffin-embedded Skeletal Muscle , using DNA polymerase gamma(TA308753) antibody(10 ug/ml).
IF Image
Immunofluorescence analysis of methanol-fixed HeLa, using DNA polymerase gamma(TA308753) antibody at 1:200 dilution.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title