Home Antibody All anti-POLG antibodies
Also for POLG (NM_001126131)
|779 - 1201 of Human POLG|
|WB, IHC, IF
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography. (Protein A or G Sepharose)
|Homo sapiens polymerase (DNA directed), gamma (POLG), transcript variant 2|
|MDP1; MIRAS; MTDPS4A; MTDPS4B; PEO; POLG1; POLGA; SANDO; SCAE|
|Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]|
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A: MCF-7 (anti-POLG antibody diluted at 1:1000)
Immunohistochemical analysis of paraffin-embedded Skeletal Muscle , using DNA polymerase gamma(anti-POLG antibody) antibody(10 ?g/ml).
Immunofluorescence analysis of methanol-fixed HeLa, using DNA polymerase gamma(anti-POLG antibody) antibody at 1:200 dilution.