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Home Antibody All anti-PKLR antibodies

Anti-PKLR Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308453
  • Rabbit Polyclonal antibody to Pyruvate Kinase (liver/RBC) (pyruvate kinase, liver and RBC)
100ul 325 3-7 Days
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 230 of Pyruvate Kinase(liver/RBC)
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB:1:1000-1:10000; IHC:1:500; IF:1:100-1:200;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens pyruvate kinase, liver and RBC (PKLR), transcript variant 2
Alternative NamePK1; PKL; PKR; PKRL; RPK
Database LinkNP_870986
FunctionThe protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate) A: H1299 B: Hela (anti-PKLR antibody diluted at 1:5000)
IHC Image
Immunohistochemical analysis of paraffin-embedded NCIN87 xenograft, using Pyruvate Kinase (liver/RBC)(anti-PKLR antibody) antibody at 1:500 dilution.
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed A431, using Pyruvate Kinase(liver/RBC)(anti-PKLR antibody) antibody at 1:200 dilution.

 

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