Home Antibody All anti-PKLR antibodies
Also for PKLR (NM_181871)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 230 of Pyruvate Kinase(liver/RBC)|
|WB, IHC, IF
||WB:1:1000-1:10000; IHC:1:500; IF:1:100-1:200;
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography. (Protein A or G Sepharose)
|Homo sapiens pyruvate kinase, liver and RBC (PKLR), transcript variant 2|
|PK1; PKL; PKR; PKRL; RPK|
|The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
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Sample (30 ug of whole cell lysate) A: H1299 B: Hela (anti-PKLR antibody diluted at 1:5000)
Immunohistochemical analysis of paraffin-embedded NCIN87 xenograft, using Pyruvate Kinase (liver/RBC)(anti-PKLR antibody) antibody at 1:500 dilution.
Immunofluorescence analysis of paraformaldehyde-fixed A431, using Pyruvate Kinase(liver/RBC)(anti-PKLR antibody) antibody at 1:200 dilution.