Home Antibody All anti-PKD2 antibodies
Also for PKD2 (NM_000297)
|Peptide with sequence C-ERAKLKRREVLGR, from the internal region of the protein sequence according to NP_000288.1.|
|Test: Human. Expected from seq similarity: Human, Mouse, Rat, Cow
||Lot dependent; please refer to CoA along with shipment
|0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.
|Homo sapiens polycystic kidney disease 2 (autosomal dominant) (PKD2)|
|APKD2; Pc-2; PC2; PKD4; TRPP2|
Entrez Gene 5311 Human
Entrez Gene 18764 Mouse
Entrez Gene 498328 Rat
|This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. The encoded protein may function in renal tubular development, morphology, and function, and may modulate intracellular calcium homoeostasis and other signal transduction pathways. This protein interacts with polycystin 1 to produce cation-permeable currents. Mutations in this gene have been associated with autosomal dominant polycystic kidney disease. [provided by RefSeq]. |
|Ion Channels: Transient receptor potentialTransmembraneDruggable Genome |
* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
TA305931 (1ug/ml) staining of HeLa lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.