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Home Antibody All anti-PIK3CG antibodies

Anti-PIK3CG TRUEMAB Antibody Clone OTI4D3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA505224 PIK3CG mouse monoclonal antibody, clone OTI4D3 (formerly 4D3) 100ul $325 In Stock
LC419184 PIK3CG HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF505224 Carrier-free (BSA/glycerol-free) PIK3CG mouse monoclonal antibody, clone OTI4D3 (formerly 4D3) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(2)
IHC(3)
IF(1)
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Also for PIK3CG (NM_002649)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human PIK3CG(NP_002640) produced in HEK293T cell.
Clone NameClone OTI4D3 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC, IF Suggested Dilutions WB 1:200~2000, IHC 1:150, IF 1:100,
Predicted MW Explanation 126.3 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma (PIK3CG), transcript variant 1
Alternative Namep110gamma; p120-PI3K; PI3CG; PI3K; PI3Kgamma; PIK3
Database LinkNP_002640
Entrez Gene 5294 Human
FunctionThis gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. [provided by RefSeq, Jul 2008].
Related PathwayES Cell Differentiation/IPSDruggable Genome Inositol phosphate metabolismErbB signaling pathwayChemokine signaling pathwayPhosphatidylinositol signaling systemmTOR signaling pathwayApoptosisMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PIK3CG (RC207790, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PIK3CG.
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Western blot analysis of extracts (35ug) from 9 different cell lines by usin g anti-PIK3CG monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
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Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-PIK3CG mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505224)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-PIK3CG mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505224)
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Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-PIK3CG mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505224)
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Anti-PIK3CG mouse monoclonal antibody (TA505224) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PIK3CG(RC207790).
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