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Anti-PIK3CB Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA308795 Rabbit Polyclonal antibody to PI3 kinase p110 beta (phosphoinositide-3-kinase, catalytic, beta polypeptide) 100ul $325 3 Weeks
LC416798 PIK3CB HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 509 and 820 of PI3 kinase p110 beta (Uniprot ID#P42338)
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1mg/ml
Guaranteed Application *WB, IF Suggested DilutionsICC/IF:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 123kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta (PIK3CB), transcript variant 1
Alternative NameP110BETA; PI3K; PI3KBETA; PIK3C1
Database LinkNP_006210
Entrez Gene 5291 Human
Entrez Gene 74769 Mouse
FunctionPhosphoinositide 3-kinases (PI3Ks) phosphorylate the 3-prime OH position of the inositol ring of inositol lipids. They have been implicated as participants in signaling pathways regulating cell growth by virtue of their activation in response to various mitogenic stimuli. PI3Ks are composed of a 110-kD catalytic subunit, such as PIK3CB, and an 85-kD adaptor subunit (Hu et al., 1993 [PubMed 8246984]).[supplied by OMIM]
Related PathwayDruggable Genome Inositol phosphate metabolismErbB signaling pathwayChemokine signaling pathwayPhosphatidylinositol signaling systemmTOR signaling pathwayApoptosisMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (50 ug of whole cell lysate). A: C2C12. B: C2C12+AEA10mM. TA308795 diluted at 1:1000.

WB Image
PI3K p110 beta antibody [N3C2], Internal detects PIK3CB protein by Western blot analysis. A. 30 ug PC-12 whole cell lysate/extract. 5 % SDS-PAGE. PI3K p110 beta antibody [N3C2], Internal (TA308795) dilution: 1:1000

WB Image
Sample (30 ug of whole cell lysate). A: H1299. 7.5% SDS PAGE. TA308795 diluted at 1:1000.

IF Image
Immunofluorescence analysis of methanol-fixed HeLa, using PI3K p110 beta(TA308795) antibody at 1:200 dilution.


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