Home Antibody All anti-PFKL antibodies
Also for PFKL (NM_001002021)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 475 and 691 of PFKL|
|WB, IHC, IF
||WB:1:500-1:3000; IHC:1:500; IF:1:100-1:500;
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens phosphofructokinase, liver (PFKL), transcript variant 1|
|ATP-PFK; PFK-B; PFK-L|
Entrez Gene 5211 Human
|Phosphofructokinase (PFK) is a tetrameric enzyme that catalyzes a key step in glycolysis, namely the conversion of D-fructose 6-phosphate to D-fructose 1,6-bisphosphate. Separate genes encode a muscle subunit (M) and a liver subunit (L). PFK from muscle is a homotetramer of M subunits, PFK from liver is a homotetramer of L-subunits, while PFK from platelets can be composed of any tetrameric combination of M and L subunits. The protein encoded by this gene represents the L subunit. Alternate splicing results in two transcript variants, one of which is a candidate for nonsense-mediated decay (NMD). [provided by RefSeq]|
|Druggable Genome Glycolysis / GluconeogenesisPentose phosphate pathwayFructose and mannose metabolismGalactose metabolismMetabolic pathways|
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Sample (30 ug of whole cell lysate) A: HepG2 (anti-PFKL antibody diluted at 1:1000)
Immunohistochemical analysis of paraffin-embedded SW480 xenograft, using PFKL(anti-PFKL antibody) antibody at 1:500 dilution.
Immunofluorescence analysis of paraformaldehyde-fixed A549, using PFKL(anti-PFKL antibody) antibody at 1:200 dilution.