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Anti-PF4 Antibody EPR7763
|A synthetic peptide corresponding to residues in human PF4 was used as an immunogen.|
||0.5~1.0 mg/ml (Lot Dependent)
|WB, ASSAY, IHC
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant (Protein A or G Sepharose)
|Does not react with Mouse
|Homo sapiens platelet factor 4 (PF4)|
|CXCL4; PF-4; SCYB4|
|PF4, or Platelet factor-4, is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair (1).|
Cytokine-cytokine receptor interaction
Signaling by GPCR
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Western blot - Anti-PF4 antibody [EPR7763]; All lanes : Anti-PF4 antibody [EPR7763] at 1/1000 dilution.Lane 1 : Human spleen lysates.Lane 2 : Human platelet lysates.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 11 kDa.
Other-Anti-PF4 antibody [EPR7763](ab129183); Equilibrium disassociation constant (KD)..
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PF4 antibody [EPR7763]; ab129183, at a 1/100 dilution, staining PF4 in paraffin embedded Human spleen tissue by Immunohistochemistry.