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Home Antibody All anti-PF4 antibodies

Anti-PF4 Antibody EPR7763

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA310753
  • Rabbit Monoclonal antibody against PF4
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400930) , 20ug Explanation
100ul 325 In Stock
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WB(1)
IHC(1)
Assay(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human PF4 was used as an immunogen.
Clone NameEPR7763 IsotypeIgG
Species ReactivityRat, Human (Does not react with: Mouse) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250
Predicted MW Explanation 11 kDa
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Does not react with Mouse

Reference Data

Target NameHomo sapiens platelet factor 4 (PF4)
Alternative NameCXCL4; PF-4; SCYB4
Database LinkNP_002610
Entrez Gene 5196 Human
Entrez Gene 360918 Rat
FunctionPF4, or Platelet factor-4, is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair (1).
Related PathwaySecreted ProteinTransmembraneDruggable Genome Cytokine-cytokine receptor interactionChemokine signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-PF4 antibody [EPR7763]; All lanes : Anti-PF4 antibody [EPR7763] at 1/1000 dilution.Lane 1 : Human spleen lysates.Lane 2 : Human platelet lysates.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 11 kDa.
Assay Image
Other-Anti-PF4 antibody [EPR7763](TA310753); Equilibrium disassociation constant (KD)..
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PF4 antibody [EPR7763]; TA310753, at a 1/100 dilution, staining PF4 in paraffin embedded Human spleen tissue by Immunohistochemistry.

 

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