Home Antibody All anti-PEX19 antibodies
Also for PEX19 (NM_001131039)
|Recombinant fragment corresponding to a region within amino acids 1 and 299 of PEX19 (Uniprot ID#P40855)|
|WB, IHC, IF
||ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:1000-1:10000
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens peroxisomal biogenesis factor 19 (PEX19), transcript variant 2|
|D1S2223E; FLJ55296; HK33; PMP1; PMPI; PXF; PXMP1; HK33; PMP1; PMPI; PXF; PXMP1; OTTHUMP00000031848; housekeeping gene, 33kD; peroxisomal farnesylated protein; peroxisomal biogenesis factor 19|
Entrez Gene 5824 Human
Entrez Gene 19298 Mouse
|This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause Zellweger syndrome (ZWS). [provided by RefSeq]|
|Druggable Genome |
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Sample (30 ug of whole cell lysate). A: Raji. B: K562. C: THP-1. D: NCI-H929. 12% SDS PAGE. TA307905 diluted at 1:10000.
Sample (50 ug of whole cell lysate). A: mouse liver. 12% SDS PAGE. TA307905 diluted at 1:10000.
PEX19 antibody detects PEX19 protein by Western blot analysis. A. 30 ug PC-12 whole cell lysate/extract. B. 30 ug Rat-2 whole cell lysate/extract. 10 % SDS-PAGE. PEX19 antibody (TA307905) dilution: 1:1000
Immunohistochemical analysis of paraffin-embedded SW480 xenograft, using PEX19(TA307905) antibody at 1:500 dilution.
Confocal immunofluorescence analysis (Olympus FV10i) of methanol-fixed HeLa, using PEX19(TA307905) antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with anti-alpha tubulin antibody (Red) at 1:2000.