OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-PDZK1 antibodies

Anti-PDZK1 Antibody EPR3751

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307425
  • Rabbit monoclonal antibody against PDZK1 (clone EPR3751 )
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400926) , 20ug
100ul $325 3-7 Days
Add to Shopping Cart
WB(1)
IHC(1)
IF(1)
spacer
Also for PDZK1 (NM_002614)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human PDZK1 was used as an immunogen.
Clone NameEPR3751 IsotypeIgG
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC, IF Suggested DilutionsFC: 1:50, ICC: 1:100 - 250, IHC: 1:100 - 250, IP: 1:50, WB: 1:5,000 - 10,000,
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens PDZ domain containing 1 (PDZK1), transcript variant 1
Alternative NameCAP70; CLAMP; NHERF-3; NHERF3; PDZD1
Database LinkNP_002605
FunctionPDZ domain-containing protein 1 (PDZK1) is a scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells (1). PDZK1 is suggested to play multiple roles in normal physiology and may influence associated disorders. It is involved in maintaining hepatic SR-BI levels and controlling HDL metabolism, protects against the development of atherosclerosis and also mediates SR-BI-dependent regulation of endothelial cell biology by HDL (2). PDZK1 expression is limited to epithelial cells, located in the kidney, pancreas, liver, and small intestine. It is also expressed at a lower level in the adrenal cortex, testis and stomach, and it is over-expressed in breast, renal and lung carcinomas (1).
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - PDZK1 antibody [EPR3751]; All lanes : Anti-PDZK1 antibody [EPR3751] at 1/5000 dilution.Lane 1 : Human fetal liver lysate.Lane 2 : Human fetal kidney lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 57 kDa.Observed band size : 70 kDa .
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PDZK1 antibody [EPR3751]; TA307425 at 1/100 dilution staining PDZK1 in Human kidney tissue by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.
IF Image
Immunocytochemistry/ Immunofluorescence - PDZK1 antibody [EPR3751]; TA307425 at 1/100 staining PDZK1 in HeLa cells by Immunofluorescence.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title