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Home Antibody All anti-PDZK1 antibodies

Anti-PDZK1 Antibody EPR3751

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307425
  • Rabbit monoclonal antibody against PDZK1 (clone EPR3751 )
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400926) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for PDZK1 (NM_002614)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human PDZK1 was used as an immunogen.
Clone NameEPR3751 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsFC: 1:50, ICC: 1:100 - 250, IHC: 1:100 - 250, IP: 1:50, WB: 1:5,000 - 10,000,
Predicted MW Explanation 57 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens PDZ domain containing 1 (PDZK1), transcript variant 1
Alternative NameCAP70; CLAMP; NHERF-3; NHERF3; PDZD1
Database LinkNP_002605
Entrez Gene 5174 Human
FunctionPDZ domain-containing protein 1 (PDZK1) is a scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells (1). PDZK1 is suggested to play multiple roles in normal physiology and may influence associated disorders. It is involved in maintaining hepatic SR-BI levels and controlling HDL metabolism, protects against the development of atherosclerosis and also mediates SR-BI-dependent regulation of endothelial cell biology by HDL (2). PDZK1 expression is limited to epithelial cells, located in the kidney, pancreas, liver, and small intestine. It is also expressed at a lower level in the adrenal cortex, testis and stomach, and it is over-expressed in breast, renal and lung carcinomas (1).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - PDZK1 antibody [EPR3751]; All lanes : Anti-PDZK1 antibody [EPR3751] at 1/5000 dilution.Lane 1 : Human fetal liver lysate.Lane 2 : Human fetal kidney lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 57 kDa.Observed band size : 70 kDa .
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PDZK1 antibody [EPR3751]; TA307425 at 1/100 dilution staining PDZK1 in Human kidney tissue by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.
IF Image
Immunocytochemistry/ Immunofluorescence - PDZK1 antibody [EPR3751]; TA307425 at 1/100 staining PDZK1 in HeLa cells by Immunofluorescence.

 

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