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Home Antibody All anti-PDE1B antibodies

Anti-PDE1B TRUEMAB Antibody Clone OTI1D6

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA503336 PDE1B mouse monoclonal antibody, clone OTI1D6 (formerly 1D6) 100ul $325 In Stock
LC400337 PDE1B HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF503336 Carrier-free (BSA/glycerol-free) PDE1B mouse monoclonal antibody, clone OTI1D6 (formerly 1D6) 100ug $450 3-4 weeks
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WB(1)
IF(1)
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Also for PDE1B (NM_000924)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human PDE1B(NP_000915) produced in HEK293T cell.
Clone NameClone OTI1D6 IsotypeIgG2b
Species ReactivityHuman Concentration0.74 mg/ml
Guaranteed Application *WB, IF Suggested Dilutions WB 1:2000, IF 1:100,
Predicted MW Explanation 61.2 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens phosphodiesterase 1B, calmodulin-dependent (PDE1B), transcript variant 1
Alternative NamePDE1B1; PDES1B
Database LinkNP_000915
Entrez Gene 5153 Human
FunctionThe protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011].
Related PathwayDruggable Genome Purine metabolismCalcium signaling pathwayProgesterone-mediated oocyte maturation

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDE1B (RC206588, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PDE1B.
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Anti-PDE1B mouse monoclonal antibody (TA503336) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PDE1B(RC206588).
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