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Home Antibody All anti-PDCD1 antibodies

Anti-PDCD1 Antibody 7A11B1

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319692
  • Mouse PD-1 / CD279 Monoclonal Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401555) , 20ug
100ug 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for PDCD1 (NM_005018)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA ~150 amino acid recombinant protein from near the terminus terminus of mouse PD-1.
Clone Name7A11B1 IsotypeIgG1
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 ug/ml, IHC: 2.5 ug/ml, IF: 20 ug/ml
BufferPD-1 Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.
Purification PD-1 Monoclonal Antibody is immunoaffinity chromotography purified IgG.

Reference Data

Target NameHomo sapiens programmed cell death 1 (PDCD1)
Alternative NameCD279; hPD-1; hPD-l; hSLE1; PD-1; PD1; SLEB2
Database LinkNP_005009
FunctionPD-1 Monoclonal Antibody: Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of "danger signals" such as LPS or other molecules associated with bacteria or other pathogens. Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases. Despite its predicted molecular weight, PD-1 often migrates at higher molecular weight in SDS-PAGE.
Related Pathway

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WB Image
Western blot analysis of PD-1 in A-20 cell lysate with PD-1 antibody at 1 ug/mL in the (A) absence and (B) presence of blocking recombinant protein.</title><style>.an6q{position:absolute;clip:rect(487px,auto,auto,487px);}</style><div class=an6q>According to your current <a href=http://paydayloansforsure.com >need cash now</a> you really look at.</div>
IHC Image
Immunohistochemistry of PD-1 in mouse brain tissue with PD-1 antibody at 2.5 ug/mL.</title><style>.an6q{position:absolute;clip:rect(487px,auto,auto,487px);}</style><div class=an6q>According to your current <a href=http://paydayloansforsure.com >need cash now</a> you really look at.</div>
IF Image
Immunofluorescence of PD-1 in mouse brain tissue with PD-1 antibody at 20 ug/mL.</title><style>.an6q{position:absolute;clip:rect(487px,auto,auto,487px);}</style><div class=an6q>According to your current <a href=http://paydayloansforsure.com >need cash now</a> you really look at.</div>

 

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