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Home Antibody All anti-PCBP2 antibodies

Anti-PCBP2 Antibody

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SKU Description Amount Price Availability*  
TA308000
  • Rabbit polyclonal antibody to PCBP2 (poly(rC) binding protein 2)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC417574) , 20ug Explanation
100ul $325 3-7 Days

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(1)
IF(1)
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Also for PCBP2 (NM_005016)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenSynthetic peptide corresponding to a region within amino acids 302 and 365 of PCBP2 (Uniprot ID#Q15366)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Rat, Xenopus laevis, Pig, Bovine) Concentration0.25mg/ml
Guaranteed Application *WB, IF Suggested DilutionsICC/IF:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 38kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (100%), Rat (100%), Xenopus laevis (93%), Pig (100%), Bovine (100%)

Reference Data

Target NameHomo sapiens poly(rC) binding protein 2 (PCBP2), transcript variant 1
Alternative NamehnRNP-E2; HNRNPE2; HNRPE2
Database LinkNP_005007
Entrez Gene 5094 Human
Entrez Gene 18521 Mouse
Entrez Gene 363005 Rat
FunctionThe protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. Thsi gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Related Pathway

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Sample (30 ug of whole cell lysate). A: Hep G2 . 10% SDS PAGE. TA308000 diluted at 1:500
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Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using PCBP2(TA308000) antibody at 1:200 dilution.
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