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Home Antibody All anti-PAK1 antibodies

Anti-PAK1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303131
  • Goat Polyclonal Antibody against PAK1
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC426982) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
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Also for PAK1 (NM_001128620)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

Immunogen Peptide with sequence C-NTEKQKKKPKMSDE, from the internal region of the protein sequence according to NP_002567.3.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human, Mouse, Rat. Expected from seq similarity: Human, Mouse, Rat, Dog Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:4,000. WB: 1-3µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens p21 protein (Cdc42/Rac)-activated kinase 1 (PAK1), transcript variant 1
Alternative NamePAKalpha
Database LinkNP_001122092
Entrez Gene 5058 Human
Entrez Gene 18479 Mouse
Entrez Gene 29431 Rat
Entrez Gene 607885 Dog
FunctionPAK proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. These proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK1 regulates cell motility and morphology. Alternativelt spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Related PathwayProtein KinaseStem cell - PluripotencyDruggable Genome MAPK signaling pathwayErbB signaling pathwayChemokine signaling pathwayAxon guidanceFocal adhesionNatural killer cell mediated cytotoxicityMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA303131 (1µg/ml) staining of Rat Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

 

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