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Home Antibody All anti-ORAI2 antibodies

Anti-ORAI2 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA306419 Rabbit Polyclonal ORAI2 Antibody 100ug $325 3-7 Days
LC426680 ORAI2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IF(1)

OriGene Data

ImmunogenORAI2 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human ORAI2.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 - 4 ug/ml, ICC: 5 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens ORAI calcium release-activated calcium modulator 2 (ORAI2), transcript variant 1
Alternative NameC7orf19; CBCIP2; MEM142B; TMEM142B
Database LinkNP_001119812
Entrez Gene 80228 Human
Entrez Gene 269717 Mouse
FunctionAntigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI2 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. Like ORAI1, ORAI2 has been shown to function as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor, although at a lesser efficacy than ORAI1. This antibody is predicted to have no cross-reactivity to ORAI1 or ORAI3.
Related PathwayTransmembrane

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of ORAI2 in Jurkat cell lysate with ORAI2 antibody at (A) 1, (B) 2 and (C) 4 ug/mL.
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Immunocytochemistry of ORAI2 in Jurkat cells with ORAI2 antibody at 5 ug/mL.
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