Home Antibody All anti-OGT antibodies
|Peptide with sequence C-YEHPKDLKLSDGR, from the internal region of the protein sequence according to NP_858058.1; NP_858059.1.|
|Test: Mouse, Rat. Expected from seq similarity: Human, Mouse, Rat, Dog
||ELISA: 1:64,000. WB: 0.05-0.2µg/ml.An
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
|Homo sapiens O-linked N-acetylglucosamine (GlcNAc) transferase (OGT), transcript variant 1|
Entrez Gene 8473 Human
Entrez Gene 108155 Mouse
Entrez Gene 26295 Rat
Entrez Gene 480955 Dog
|O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT) catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains nine tetratricopeptide repeats and a putative bipartite nuclear localization signal. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq]. |
|Druggable Genome O-Glycan biosynthesisMetabolic pathways|
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TA302556 (0.05µg/ml) staining of Rat Pancreas lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.