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Home Antibody All anti-NSMAF antibodies

Anti-NSMAF Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308550
  • Rabbit polyclonal antibody to FAN (neutral sphingomyelinase (N-SMase) activation associated factor)
100ul 325 3-7 Days
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WB(1)
IHC(1)

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 262 and 570 of FAN (Uniprot ID#Q92636)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Rat) Concentration0.93mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsIHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 104kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (93%), Rat (91%)

Reference Data

Target NameHomo sapiens neutral sphingomyelinase (N-SMase) activation associated factor (NSMAF), transcript variant 2
Alternative NameFAN
Database LinkNP_001138244
Entrez Gene 8439 Human
Entrez Gene 18201 Mouse
Entrez Gene 353233 Rat
FunctionThis gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western Blot analysis of NSMAF expression in transfected 293T cell line by NSMAF polyclonal antibody. A: Non-transfected lysate. B: NSMAF transfected lysate. 7.5% SDS PAGE. TA308550 diluted at 1:500
IHC Image
Immunohistochemical analysis of paraffin-embedded T(gastric CA) , using NSMAF(TA308550) antibody at 1:100 dilution.

 

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