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Home Antibody All anti-NR5A2 antibodies

Anti-NR5A2 Antibody EPR7000


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA310732 Rabbit Monoclonal antibody against NR5A2 100ul $325 In Stock
LC401255 NR5A2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human NR5A2 was used as an immunogen.
Clone NameEPR7000 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000
Predicted MW Explanation 61 kDa
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens nuclear receptor subfamily 5, group A, member 2 (NR5A2), transcript variant 2
Alternative NameB1F; B1F2; CPF; FTF; FTZ-F1; FTZ-F1beta; hB1F-2; LRH-1; LRH1
Database LinkNP_003813
Entrez Gene 2494 Human
Entrez Gene 26424 Mouse
Entrez Gene 60349 Rat
FunctionNR5A2 is a nuclear receptor originally identified in the liver and mostly known for its regulatory role in cholesterol and bile acid homeostasis. It is a key regulator of intestinal function, coordinating unanticipated actions, such as cell renewal and local immune function with important implications to common intestinal diseases, including colorectal cancer and inflammatory bowel disease. Unlike most of the other nuclear receptors, liver NR5A2 acts as a constitutively active transcription factor (1). Furthermore, NR5A2 functions in steroidogenesis in the gonad and intestine (2).
Related PathwayNuclear Hormone ReceptorTranscription FactorsDruggable Genome Maturity onset diabetes of the young

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-NR5A2 / LRH1 antibody [EPR7000]; All lanes : Anti-NR5A2 / LRH1 antibody [EPR7000] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : BxPC3 cell lysate.Lane 3 : HepG2 cell lysate.Lane 4 : MCF7 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti rabbit at 1/2000 dilution.Predicted band size : 61 kDa.Observed band size : 65 kDa .


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