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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]
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 Home All anti-NR3C1 antibodies

Anti-NR3C1 Antibody EPR4595

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SKU Description Amount Price Availability*  
TA311010
  • Rabbit Monoclonal antibody against Glucocorticoid Receptor (NR3C1)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC424874) , 20ug
 100ul $325 3-7 Days Add to Shopping Cart
WB(1)
Gene NameHomo sapiens nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) (NR3C1), transcript variant 1
Synonyms:GCCR; GCR; GR; GRL
ImmunogenA recombinant protein fragment corresponding to amino acids 2-149 of human Glucocorticoid Receptor was used as an immunogen.
BufferStore at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Clone NameEPR4595 Isotype
Species ReactivityHuman, Mouse, Rat Concentration
Guaranteed Application *WB Suggested DilutionsWB: 1:1,000 - 10,000;
BackgroundGlucocorticoid Receptor can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. It is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in Glucocorticoid Receptor are a cause of glucocorticoid resistance, or cortisol, resistance (1).
Related Pathway
Adipogenesis

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WB Image
Western blot analysis on (A) HeLa, (B) A431, (C) Jurkat, and (D) HepG2 cell lysates using anti-Glucocorticoid Receptor RabMAb.

 

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