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Anti-NR2E1 Antibody EPR4491


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SKU Description Amount Price Availability*  
  • Rabbit Monoclonal antibody against NR2E1
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC418799) , 20ug Explanation
100ul $325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human NR2E1 was used as an immunogen.
Clone NameEPR4491 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY Suggested DilutionsWB: 1:1000 - 1:10000
Predicted MW Explanation 43 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens nuclear receptor subfamily 2, group E, member 1 (NR2E1), transcript variant 2
Alternative NameTLL; TLX; XTLL
Database LinkNP_003260
Entrez Gene 7101 Human
Entrez Gene 21907 Mouse
Entrez Gene 684085 Rat
FunctionNR2E1 is an orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity. NR2E1 is required for brain development, and it is also involved in the regulation of retinal development (1). It is also an essential regulator of neural stem cell self-renewal, maintaining adult neural stem cells in an undifferentiated and self-renewable state (2).
Related PathwayNuclear Hormone ReceptorTranscription FactorsDruggable Genome

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* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - NR2E1 / Tailless antibody [EPR4491]; All lanes : Anti-NR2E1 / Tailless antibody [EPR4491] at 1/1000 dilution.Lane 1 : Fetal brain lysate.Lane 2 : Human hippocampus lysate.Lane 3 : SH-SY5Y lysate.Lane 4 : Jurkat lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 43 kDa.
Other-Anti-NR2E1 / Tailless antibody [EPR4491](TA310731); Equilibrium disassociation constant (KD)..


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