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Anti-NR2E1 Antibody EPR4491
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Also for NR2E1 (NM_003269)
|A synthetic peptide corresponding to residues in human NR2E1 was used as an immunogen.|
|Human, Mouse, Rat
||WB: 1:1,000 - 10,000;
|Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.|
|Homo sapiens nuclear receptor subfamily 2, group E, member 1 (NR2E1)|
|TLL; TLX; XTLL|
|NR2E1 is an orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity. NR2E1 is required for brain development, and it is also involved in the regulation of retinal development (1). It is also an essential regulator of neural stem cell self-renewal, maintaining adult neural stem cells in an undifferentiated and self-renewable state (2).|
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Western blot analysis on (A) fetal brain, (B) human hippocampus, (C) SH-SY5Y, and (D) Jurkat lysates using anti-NR2E1 RabMAb.