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Home Antibody All anti-NR0B2 antibodies

Anti-NR0B2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308392
  • Rabbit Polyclonal antibody to NR0B2 (nuclear receptor subfamily 0, group B, member 2)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402893) , 20ug
100ul 325 In Stock
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WB(1)
IHC(1)
IF(1)
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Also for NR0B2 (NM_021969)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 64 and 246 of NR0B2
Clone Name IsotypeIgG
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB:1:500-1:3000; IHC:1:100; IF:1:100-1:500;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens nuclear receptor subfamily 0, group B, member 2 (NR0B2)
Alternative NameSHP; SHP1
Database LinkNP_068804
FunctionThe protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function. [provided by RefSeq]
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
A: Molt-4 (anti-NR0B2 antibody diluted at 1:1000)
IHC Image
Immunohistochemical analysis of paraffin-embedded SW480 Xenograft, using NR0B2(anti-NR0B2 antibody) antibody at 1:100 dilution.
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed A431, using NR0B2(anti-NR0B2 antibody) antibody at 1:500 dilution.

 

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