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Home Antibody All anti-NPR3 antibodies

Anti-NPR3 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA308692 Rabbit polyclonal antibody to NPR-C (natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)) 100ul $325 3-7 Days
LC424462 NPR3 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(2)
IF(2)

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 265 and 514 of NPR-C
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Rat, Xenopus laevis) Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:5000-1:20000
Predicted MW Explanation 60kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Rat (96%), Xenopus laevis (82%)

Reference Data

Target NameHomo sapiens natriuretic peptide receptor 3 (NPR3), transcript variant 2
Alternative NameANP-C; ANPR-C; ANPRC; C5orf23; GUCY2B; NPR-C; NPRC
Database LinkNP_000899
Entrez Gene 4883 Human
Entrez Gene 25339 Rat
FunctionThe family of natriuretic peptides (see MIM 108780) elicit a number of vascular, renal, and endocrine effects that are important in the maintenance of blood pressure and extracellular fluid volume. These effects are mediated by specific binding of the peptides to cell surface receptors in the vasculature, kidney, adrenal, and brain.[supplied by OMIM]
Related PathwayTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample (30 ug of whole cell lysate). A: Hep G2 . 7.5% SDS PAGE. TA308692 diluted at 1:10000
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NPR-C antibody [N3C3] detects NPR-C protein at cytosol on mouse testis by immunohistochemical analysis. Sample: Paraffin-embedded mouse testis. NPR-C antibody [N3C3] (TA308692) dilution: 1:500.
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Immunohistochemical analysis of paraffin-embedded U87 xenograft, using NPR-C (TA308692) antibody at 1:500 dilution.
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NPR-C antibody [N3C3] detects NPR-C protein at cytoplasm by immunofluorescent analysis. Sample: A431 cells were fixed in ice-cold MeOH for 5 min. Green: NPR-C protein stained by NPR-C antibody [N3C3] (TA308692) diluted at 1:500. Blue: Hoechst 33342 staini
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Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using NPR-C (TA308692) antibody at 1:200 dilution.
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